An alert observation (templateId 2.16.840.1.113883.10.20.1.18) SHALL be represented with Observation. The value for “Observation / moodCode” in an alert observation SHALL be “EVN” 2.16.840.1.113883.5.1001 ActMood STATIC. An alert observation SHALL include exactly one Observation / statusCode. The value for “Observation / statusCode” in an alert observation SHALL be “completed” 2.16.840.1.113883.5.14 ActStatus STATIC. An agent participation in an alert observation SHALL contain exactly one participant / participantRole / playingEntity. value for Observation / participant / typeCode in an agent participation SHALL be “CSM” “Consumable” 2.16.840.1.113883.5.90 ParticipationType STATIC. The value for Observation / participant / participantRole / classCode in an agent participation SHALL be “MANU” “Manufactured” 2.16.840.1.113883.5.110 RoleClass STATIC. The value for Observation / participant / participantRole / playingEntity / classCode in an agent participation SHALL be “MMAT” “Manufactured material” 2.16.840.1.113883.5.41 EntityClass STATIC. An agent participation in an alert observation SHALL contain exactly one participant / participantRole / playingEntity / code. The value for “entryRelationship / typeCode” in a relationship between an alert observation and reaction observation SHALL be “MFST” “Is manifestation of” 2.16.840.1.113883.5.1002 ActRelationshipType STATIC. An alert observation SHOULD contain at least one Observation / participant, representing the agent that is the cause of the allergy or adverse reaction. The value for “participant / participantRole / playingEntity / code” in an agent participation SHOULD be selected from the RxNorm (2.16.840.1.113883.6.88) code system for medications, and from the CDC Vaccine Code (2.16.840.1.113883.6.59) code system for immunizations.